ARN-3236|cas 1613710-01-2|DC Chemicals

Cas No.:	1613710-01-2
Chemical Name:	3-(2,4-Dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
Synonyms:	GTPL9581;example 86 [WO2014093383];3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine;ARN-3236
SMILES:	S1C([H])=C([H])C(=C1[H])C1C([H])=C([H])N=C2C=1C(=C([H])N2[H])C1C([H])=C([H])C(=C([H])C=1OC([H])([H])[H])OC([H])([H])[H]
Formula:	C₁₉H₁₆N₂O₂S
M.Wt:	336.4075
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) (IC50 <1 nM), with activity in inhibiting growth and enhancing paclitaxel sensitivity in cultures and xenografts of ovarian cancer cell lines[1][2].

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC10778	YKL-06-061	YKL-06-061 is a potent and selective SIK (salt-inducible kinase) inhibitor.
DC10824	ARN-3236	ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.