Cas No.: | |
Chemical Name: | AT-273 |
Synonyms: | AT-273;AT273;AT273 |
SMILES: | OC[C@@H]1[C@@H](O)[C@H0](F)(C)[C@H](N2C=NC3C(=O)NC(N)=NC=32)O1 |
Formula: | C11H14FN5O4 |
M.Wt: | 299.10 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Publication: | Berliba E, Bogus M, Vanhoutte F, Berghmans PJ, Good SS, Moussa A, Pietropaolo K, Murphy RL, Zhou XJ, Sommadossi JP. 2019. Safety, pharmacokinetics and antiviral activity of AT-527, a novel purine nucleotide prodrug, in HCV-infected subjects with and without cirrhosis. Antimicrob Agents Chemother 63:e01201-19. https://doi.org/10.1128/AAC.01201-19. |