Andarine (GTX-007) |cas 401900-40-1|DC Chemicals

Cas No.:	401900-40-1
Chemical Name:	Andarine
Synonyms:	Ostarine;N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropanamide;Andarine;Andarine(S-4);(2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide;(S)-3-(4-Acetylaminophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethylphenyl)propionamide;Andarine (GTX-007);MK-2866;Propanamide, 3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, (2S)-;S4 (Andarine);S-4, andarine;GTx-007;GTX007;MK2866;S-3-(4-Acetylamino-phenoxy)-2-hydroxy-2-methyl-n-(4-nitro-3-trifluoromethyl-phenyl)-propionamide;S-4;UNII-7UT2HAH49H;Andarine, S-4;SARM S-4;7UT2HAH49H;S-4 cpd;ANDARINE;S4;Andarine met;Andarine/;(S)-Andarine;ANDARINE (S4);M
SMILES:	FC(C1=C(C([H])=C([H])C(=C1[H])N([H])C([C@](C([H])([H])[H])(C([H])([H])OC1C([H])=C([H])C(=C([H])C=1[H])N([H])C(C([H])([H])[H])=O)O[H])=O)[N+](=O)[O-])(F)F
Formula:	C₁₉H₁₈F₃N₃O₆
M.Wt:	441.3579
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Andarine (S-4) is an investigational selective androgen receptor modulator (SARM) and an active partial agonist.

References:

[1]. Thevis M, Geyer H, Kamber M, Sch?nzer W.Detection of the arylpropionamide-derived selective androgen receptor modulator (SARM) S-4 (Andarine) in a black-market product.Drug Test Anal. 2009 Aug;1(8):387-92. [2]. Thevis M, Thomas A, Fussh?ller G, Beuck S, Geyer H, Sch?nzer W.Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes.Rapid Commun Mass Spectrom. 2010 Aug [3]. Thomas A, Geyer H, Sch?nzer W, Crone C, Kellmann M, Moehring T, Thevis M.Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer.Anal Bioanal Chem. 2012 May;40 [4]. Guddat S, Solymos E, Orlovius A, Thomas A, Sigmund G, Geyer H, Thevis M, Sch?nzer W.High-throughput screening for various classes of doping agents using a new 'dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approach.Drug Tes [5]. Chen J, Kim J, Dalton JT. Discovery and therapeutic promise of selective androgen receptor modulators. Mol Interv. 2005 Jun;5(3):173-88.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC10811	S23	S23 is a novel Selective Androgen Receptor Modulator(SARM)
DC4163	RU58841	RU58841 is a nonsteroidal anti-androgen with potency (IC50 = 100 nM, Ka = 1.1 nM) comparable to hydroxyflutamide.
DC9657	RAD140	RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM).
DC8248	Ostarine(MK-2286)	Ostarine(MK-2866; GTX-024)A modulator to human androgen receptor.
DC8700	ODM-201(Darolutamide)	ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells.
DC5069	Enzalutamide (MDV3100)	MDV3100 is an androgen-receptor (AR) antagonist with IC50 of 36 nM.
DC7633	Ligandrol (VK5211, LGD-4033)	LGD-4033 is a novel selective androgen receptor modulator (SARM)
DC9738	GSK2881078	GSK2881078 (GSK-2881078 ) is a selective androgen receptor modulator (SARM).
DC8856	EPI-001	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ∼6 μM and a selective PPAR-gamma modulator
DC4160	CB-03-01	CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use.

Andarine (GTX-007,S-4)