| DC10811 |
S23
|
S23 is a novel Selective Androgen Receptor Modulator(SARM) |
| DC4163 |
RU58841
|
RU58841 is a nonsteroidal anti-androgen with potency (IC50 = 100 nM, Ka = 1.1 nM) comparable to hydroxyflutamide. |
| DC9657 |
RAD140
|
RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). |
| DC8248 |
Ostarine(MK-2286)
|
Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism. |
| DC8700 |
ODM-201(Darolutamide)
|
ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells. |
| DC5069 |
Enzalutamide (MDV3100)
|
MDV3100 is an androgen-receptor (AR) antagonist with IC50 of 36 nM. |
| DC7633 |
Ligandrol (VK5211, LGD-4033)
|
Ligandrol (LGD-4033) is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity. |
| DC9738 |
GSK2881078
|
GSK-2881078 is an orally active and nonsteroidal selective androgen receptor modulator (SARM) which act as partial AR agonists in androgenic tissues while mainly as complete AR agonists in synthetic metabolic tissues,induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM) and the effect can be inhibited by the non-steroidal AR antagonist Bicalutamide. GSK-2881078 can be used in research of muscle weakness and cachexia associated with both chronic and acute illness. |
| DC8856 |
EPI-001
|
EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ∼6 μM and a selective PPAR-gamma modulator |
| DC4160 |
CB-03-01
|
CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use. |
