GSK2881078|androgen receptor modulator(SARM)

Cas No.:	1539314-06-1
Chemical Name:	GSK-2881078
Synonyms:	GSK-2881078;GSK2881078;BCP20210;GSK 2881078;1-(1-methylsulfonylpropan-2-yl)-4-(trifluoromethyl)indole-5-carbonitrile
SMILES:	S(C([H])([H])[H])(C([H])([H])C([H])(C([H])([H])[H])N1C([H])=C([H])C2C(C(F)(F)F)=C(C#N)C([H])=C([H])C1=2)(=O)=O
Formula:	C₁₄H₁₃F₃N₂O₂S
M.Wt:	330.3254
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

GSK 2881078 is a selective androgen receptor modulator potentially for the treatment of cachexia.GSK 2881078 is a selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC7633	Ligandrol (VK5211, LGD-4033)	Ligandrol (LGD-4033) is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity.
DC9738	GSK2881078	GSK-2881078 is an orally active and nonsteroidal selective androgen receptor modulator (SARM) which act as partial AR agonists in androgenic tissues while mainly as complete AR agonists in synthetic metabolic tissues,induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM) and the effect can be inhibited by the non-steroidal AR antagonist Bicalutamide. GSK-2881078 can be used in research of muscle weakness and cachexia associated with both chronic and acute illness.
DC4160	CB-03-01	CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use.