BAY-876

  Cat. No.:  DC10107   Featured
Chemical Structure
1799753-84-6
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More than 5000 active chemicals with high quality for research!
Field of application
BAY-876 is the first highly selective GLUT1 inhibitor with IC50 of 0.002 uM. show good metabolic stability in vitro and high oral bioavailability in vivo.
Cas No.: 1799753-84-6
Chemical Name: 4-N-[1-[(4-Cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicarboxamide
Synonyms: BAY-876;BAY876;N4-[1-[(4-Cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide;BAY 876;N4-(1-(4-Cyanobenzyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-7-fluoroquinoline-2,4-dicarboxamide;BCP25065;s8452;SB19770;N4-{1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}-7-fluoroquinoline-2,4-dicarboxamide;2,4-Quinoline;4-N-[1-[(4-Cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicar
SMILES: FC(C1C(=C(C([H])([H])[H])N(C([H])([H])C2C([H])=C([H])C(C#N)=C([H])C=2[H])N=1)N([H])C(C1=C([H])C(C(N([H])[H])=O)=NC2C([H])=C(C([H])=C([H])C1=2)F)=O)(F)F
Formula: C24H16F4N6O2
M.Wt: 496.4165
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: BAY-876 is the first highly selective GLUT1 inhibitor with IC50 of 0.002 uM. show good metabolic stability in vitro and high oral bioavailability in vivo.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC10493 WZB117 WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels.
DC8359 STF-31 STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake.
DC10107 BAY-876 BAY-876 is the first highly selective GLUT1 inhibitor with IC50 of 0.002 uM. show good metabolic stability in vitro and high oral bioavailability in vivo.
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