Cas No.: | 620112-78-9 |
Synonyms: | CCG 63802; CCG63802 |
SMILES: | N#C/C(C1=NC2=CC=CC=C2S1)=CC3=C(N=C4C(C)=CC=CN4C3=O)OC5=CC=CC(C)=C5 |
Formula: | C26H18N4O2S |
M.Wt: | 450.5117 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein; with greatest potency at RGS4. CCG-63802 is selective amongst RGS proteins, with greatest potency at RGS4. CCG-63802 inhibits GTPase accelerating protein activity of RGS4 and blocks its interaction with Gαo. Retains activity under reducing conditions. |