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CCG-4986

  Cat. No.:  DC11662  
Chemical Structure
7134-19-2
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More than 5000 active chemicals with high quality for research!
Field of application
A non-peptide, selective RGS4 inhibitor that inhibits RGS4/Gα(o) binding with 3 to 5 uM potency.
Cas No.: 7134-19-2
Chemical Name: Methyl-N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoate
Synonyms: CCG 4986;CCG4986
SMILES: C(S(=NS(C1=CC=C(Cl)C=C1)(=O)=O)OC)1=CC=C([N+]([O-])=O)C=C1
Formula: C13H11ClN2O5S2
M.Wt: 374.81
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A non-peptide, selective RGS4 inhibitor that inhibits RGS4/Gα(o) binding with 3 to 5 uM potency; shows selectivity for RGS4 and does not inhibit RGS8; binds to RGS4, inhibits RGS4 stimulation of Galpha(o) GTPase activity in vitro, and prevents RGS4 regulation of mu-opioid-inhibited adenylyl cyclase activity in permeabilized cells.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC9613 CCG-63808 CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.
DC9612 CCG-63802 CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein; with greatest potency at RGS4. IC50 value: Target: RGS CCG-63802 is selective amongst RGS proteins, with greatest potency at RGS4.
DC11662 CCG-4986 A non-peptide, selective RGS4 inhibitor that inhibits RGS4/Gα(o) binding with 3 to 5 uM potency.
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