CH5132799

  Cat. No.:  DC7102   Featured
Chemical Structure
1007207-67-1
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Field of application
CH5132799 selectively inhibits class I PI3Ks, such as PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ with IC50 values of 0.014, 0.12, 0.50, and 0.36 uM, respectively; shows less inhibition of class II PI3Ks, class III PI3ks, and mTOR.
Cas No.: 1007207-67-1
Chemical Name: 5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine
Synonyms: CH 5132799; CH-5132799
SMILES: CS(=O)(=O)N1CCC2=C(N=C(N=C21)N3CCOCC3)C4=CN=C(N=C4)N
Formula: C15H19N7O3S
M.Wt: 377.42
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CH5132799 inhibits class I PI3Ks, particularly PI3Kα with IC50 of 14 nM; less potent to PI3Kβδγ, while sensitive in PIK3CA mutations cell lines.For the detailed information of CH5132799, the solubility of CH5132799 in water, the solubility of CH5132799 in DMSO, the solubility of CH5132799 in PBS buffer, the animal experiment (test) of CH5132799, the cell expriment (test) of CH5132799, the in vivo, in vitro and clinical trial test of CH5132799, the EC50, IC50,and Affinity of CH5132799, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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