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Home > Inhibitors & Agonists > Cytoskeleton/Cell Adhesion Molecules > Arp2/3 complex

CK-869

  Cat. No.:  DC11475   Featured
Chemical Structure
388592-44-7
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More than 5000 active chemicals with high quality for research!
Field of application
CK-869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 388592-44-7
Chemical Name: 2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one
Synonyms: 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one;CK 869;2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone;CK-0157869;CK-869
SMILES: O=C1N(C2=CC=C(OC)C=C2OC)C(C3=CC=CC(Br)=C3)SC1
Formula: C17H16NO3Sbr
M.Wt: 394.28284
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM.
In Vitro: CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM[1]. CK-869 significantly inhibits MT polymerization even at a concentration of 25 μM[2].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC72598 EG-011 EG-011 is the first-in-class and potent Wiskott-Aldrich syndrome protein (WASP) activator. EG-011 activates the auto-inhibited form of WASP with strong actin polymerization. EG-011 has selective anti-tumor activity in lymphomas.
DC11475 CK-869 CK-869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex.
DC7386 CK-636 CK-636(CK-0944636) is a small molecule inhibitor of Arp2/3 complex; Inhibitor of actin polymerization; Cell permeable inhibitor of human (IC50=4μM), fission yeast (IC50=24μM) and bovine (IC50=32μM) Arp2/3 complex between Arp2 and Arp3.
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