Carubicin

  Cat. No.:  DC8113   Featured
Chemical Structure
50935-04-1
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Field of application
Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata.
Cas No.: 50935-04-1
Chemical Name: Carminomicin I
Synonyms: Carminomicin I;(8S-cis)-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione;5,12-Naphthacenedione, 8-acetyl-10-[[3-amino-2,3,6-trideoxy-.α.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-;Antibiotic R-588A;carminomycin I;Carubicin;Karminomitsin;Nsc 180024;50935-04-1;5, 8-acetyl-10-[[3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-;5, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetra-hydroxy- (8S-cis)-;NSC180024;5, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-;SCHEMBL1650594;CHEMBL275147;(1S,3S)-3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside;NCGC00159344-02;Carubicine [INN-French];CAS-50935-04-1;SCHEMBL9552;HY-B2171;DSSTox_GSID_22742;NS00011901;Carminomycin, O-Demethyldaunomycin, CCRIS 961;DTXCID602742;UNII-E7437K3983;BDBM50103635;CHEMBL474260;5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-;CCRIS 961;O-Demethyldaunomycin;Carubicine;CHEBI:31359;Tox21_111589;(1S,3S)-3-ACETYL-1,2,3,4,6,11-HEXAHYDRO-3,5,10,12-TETRAHYDROXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSIDE;NSC-180024;EX-A2244;50935-04-1 (free base);Carminomycin;Carubicinum [INN-Latin];(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione;Tox21_111978;Q5047474;E7437K3983;(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione;(8S,10S)-8-acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,6,8,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione;Carubicinum;(1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-tridesoxy-alpha-L-lyxo-hexopyranosid;DSSTox_CID_2742;KARMINOMYCIN;CCRIS 6185;39472-31-6;Carubicin [INN];NCGC00160675-01;5,12-NAPHTHACENEDIONE, 8-ACETYL-10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-1,6,8,11-TETRAHYDROXY-, (8S-CIS)-;Carubicina;CARUBICIN [MI];5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)-;5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)-;Carminomycin; Carubicin;DSSTox_RID_76711;AKOS040744813;A857268;CS-0021097;Antibiotic R 588A; Carminomicin I; Carminomycin I;DTXSID3022742;Car...
SMILES: O([C@]1([H])O[C@@H](C)[C@@H](O)[C@@H](N)C1)[C@H]1C[C@](O)(C(=O)C)CC2C(=C3C(C4=CC=CC(O)=C4C(=O)C3=C(O)C1=2)=O)O
Formula: C26H27NO10
M.Wt: 513.49
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. For the detailed information of Carubicin, the solubility of Carubicin in water, the solubility of Carubicin in DMSO, the solubility of Carubicin in PBS buffer, the animal experiment (test) of Carubicin, the cell expriment (test) of Carubicin, the in vivo, in vitro and clinical trial test of Carubicin, the EC50, IC50,and affinity,of Carubicin, For the detailed information of Carubicin, the solubility of Carubicin in water, the solubility of Carubicin in DMSO, the solubility of Carubicin in PBS buffer, the animal experiment (test) of Carubicin, the cell expriment (test) of Carubicin, the in vivo, in vitro and clinical trial test of Carubicin, the EC50, IC50,and affinity,of Carubicin, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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