DC-Chol

  Cat. No.:  DC36443   Featured
Chemical Structure
166023-21-8
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More than 5000 active chemicals with high quality for research!
Field of application
DC-Chol is a cationic cholesterol derivative. DC-Chol, as a component of lipoplexes with DOPE, has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice.
Cas No.: 166023-21-8
Chemical Name: Cholest-5-en-3-ol (3b)-,3-[N-[2-(dimethylamino)ethyl]carbamate], hydrochloride (1:1)
Synonyms: Cholest-5-en-3-ol (3b)-,3-[N-[2-(dimethylamino)ethyl]carbamate], hydrochloride (1:1);DC-Cholesterol;2,3-dihydroxypropyl dihydrogen phosphate- cyclohexanamine(2:1);AC1L3UOP;AR-1D2608;CTK8D6246;DC-cholesterol hydrochloride;EINECS 249-889-9;marinobufotoxin;3β-[N-(Dimethylaminoethane)­carbamoyl]­cholesterol;DC-Chol;cholesteryl 3B-(N-(dimethylaminoethyl)*carbamate);Cholesteryl 3β-N-(di-methyl-amino-ethyl)-carbamate;3β-[n-(dimethylaminoethane) carbamoyl] cholesterol;3-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol;cholesteryl 3beta-N-(dimethylaminomethyl)carbamate HCl;CHOLESTERYL N-[DIMETHYL-AMINOETHYL]CARBAMATE HYDROCHLORIDE;3β-[N-(Dimethylaminoethane)carbamoyl]cholesterol, DC-Chol;O-[(N,N-Dimethylaminoethyl)-carbamoyl]cholesterol hydrochloride;DC-Cholesterol.HCl
SMILES: Cl.CN(CCNC(OC1CCC2(C3CCC4(C(CCC4C3CC=C2C1)C(CCCC(C)C)C)C)C)=O)C
Formula: C32H56N2O2.HCl
M.Wt: 537.26018
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_18753_DC36443
COA
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Cat. No. Product name Field of application
DC70000 Lysyllysyllysine Lysyllysyllysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles.
DC33580 DODMA DODMA, also known as MBN 305A is a a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery
DC33636 DOTAP DOTAP, also known as 1,2-Dioleoyl-3-trimethylammoniumpropane, is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in gene delivery vectors for gene ther
DC46471 RP101988 RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely.
DC45184 Hydrofurimazine Hydrofurimazine is a NanoLuc substrate whose enhanced aqueous solubility allows delivery of higher doses to mice. Hydrofurimazine enables sensitive bioluminescence imaging for either prolonged light production of high sensitivity.
DC37901 PD-173212 PD-173212 is a small molecule N-type calcium channel blocker.
DC37333 N,N-Diethyl-p-toluamide N,N-Diethyl-p-toluamide is a mosquito repellent.
DC37321 AI3-15902 AI3-15902 is a biochemical.
DC37283 Methyl phenylcarbamate Methyl phenylcarbamate is a biochemical.
DC37252 Ampyrone Ampyrone is a metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.
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