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| Cas No.: | 1903768-17-1 |
| Chemical Name: | Danicopan free base |
| Synonyms: | ACH-4471;ACH4471;ACH-0144471 |
| SMILES: | N(C(CN1C2=C(C=C(C3=CN=C(C)N=C3)C=C2)C(C(C)=O)=N1)=O)1C[C@@H](F)C[C@@H]1C(NC1=NC(Br)=CC=C1)=O |
| Formula: | C26H23BrFN7O3 |
| M.Wt: | 580.418 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Danicopan, a selective and orally active small-molecule factor D inhibitor, inhibits alternative pathway of complement (APC) activity. Danicopan has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)[1]. |
| Target: | Factor D[1] |
| References: | [1]. https://www.ncbi.nlm.nih.gov/pubmed/28416568 |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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