Cas No.: | 955095-45-1 |
Chemical Name: | (R)-2-(((4-((2,2-Dimethyl-1,3-dioxan-5-yl)methoxy)-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole |
Synonyms: | E-3710;Z-215 |
SMILES: | C([S@](CC1=NC=C(C)C(OCC2COC(C)(C)OC2)=C1C)=O)1NC2=CC=CC=C2N=1 |
Formula: | C22H27N3O4S |
M.Wt: | 429.535 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM; inhibits histamine-stimulated gastric acid secretion with ED50 of 0.18-0.2 mg/kg in gastric fistula model in dogs, displays 2.3-fold more potency over Esomeprazole. |