Azeloprazole

  Cat. No.:  DC11515  
Chemical Structure
955095-45-1
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More than 5000 active chemicals with high quality for research!
Field of application
A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.
Cas No.: 955095-45-1
Chemical Name: (R)-2-(((4-((2,2-Dimethyl-1,3-dioxan-5-yl)methoxy)-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole
Synonyms: E-3710;Z-215
SMILES: C([S@](CC1=NC=C(C)C(OCC2COC(C)(C)OC2)=C1C)=O)1NC2=CC=CC=C2N=1
Formula: C22H27N3O4S
M.Wt: 429.535
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM; inhibits histamine-stimulated gastric acid secretion with ED50 of 0.18-0.2 mg/kg in gastric fistula model in dogs, displays 2.3-fold more potency over Esomeprazole.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC11546 Azeloprazole sodium A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.
DC11515 Azeloprazole A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.
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