Azeloprazole sodium |E-3710;Z-215

Cas No.:	955095-47-3
Chemical Name:	(R)-2-(((4-((2,2-Dimethyl-1,3-dioxan-5-yl)methoxy)-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole, sodium salt
Synonyms:	E-3710;Z-215
SMILES:	[Na+].C([S@](CC1=NC=C(C)C(OCC2COC(C)(C)OC2)=C1C)=O)1[N-]C2=CC=CC=C2N=1
Formula:	C₂₂H₂₇N₃NaO₄S
M.Wt:	452.525
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM; inhibits histamine-stimulated gastric acid secretion with ED50 of 0.18-0.2 mg/kg in gastric fistula model in dogs, displays 2.3-fold more potency over Esomeprazole.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC11546	Azeloprazole sodium	A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.
DC11515	Azeloprazole	A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.