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E3 Ligand-Linker Conjugate 6

  Cat. No.:  DC11572   Featured
Chemical Structure
2022182-57-4
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More than 5000 active chemicals with high quality for research!
Field of application
An E3 ligase ligand-linker conjugate for PROTAC..
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2022182-57-4
Chemical Name: N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
SMILES: C(NCCCN)(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
Formula: C18H20N4O6
M.Wt: 388.38
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: 1. Lohbeck J, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.
Description: An E3 ligase ligand-linker conjugate for PROTAC.
References: References 1. Lohbeck J, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. View Related Products by Target E3 Ligase Ligand-Linker Conjugate
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
Cat. No. Product name Field of application
DC45712 Pomalidomide-amino-PEG3-NH2 hydrochloride Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
DC45710 Pomalidomide-amino-PEG5-NH2 hydrochloride Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
DC40565 KB02-COOH KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 and KB02-SLF.
DC28654 NH2-PEG6-Boc NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC11574 E3 Ligand-Linker Conjugate 8 An E3 ligase ligand-linker conjugate for PROTAC..
DC11573 E3 Ligand-Linker Conjugate 7 An E3 ligase ligand-linker conjugate for PROTAC..
DC11572 E3 Ligand-Linker Conjugate 6 An E3 ligase ligand-linker conjugate for PROTAC..
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