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| Cas No.: | 1110873-99-8 |
| Chemical Name: | 2-(((3-methylisoxazol-5-yl)methyl)thio)-N-(2-((2-nitro-4-(trifluoromethyl)phenyl)amino)ethyl)benzamide |
| Synonyms: | RU 301;RU301 |
| SMILES: | C(NCCNC1=CC=C(C(F)(F)F)C=C1[N+]([O-])=O)(=O)C1=CC=CC=C1SCC1ON=C(C)C=1 |
| Formula: | C21H19F3N4O4S |
| M.Wt: | 480.462 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| Description: | RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1]. |
| Target: | IC50: 10 μM (TAM)[1] |
| References: | [1]. Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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