SCYX-7158|AN-5568;SCYX 7158;AN 5568;Acoziborole

Cas No.:	1266084-51-8
Chemical Name:	4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-(trifluoromethyl)benzamide
Synonyms:	AN-5568;SCYX 7158;AN 5568;Acoziborole
SMILES:	C(NC1C=C2C(=CC=1)C(C)(C)OB2O)(=O)C1=CC=C(F)C=C1C(F)(F)F
Formula:	C₁₇H₁₄BF₄NO₃
M.Wt:	367.102
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

An orally-active, CNS permeable benzoxaborole antiprotozoal agent; is active in vitro against relevant strains of Trypanosoma brucei, including T. b. rhodesiense and T. b. gambiense; is efficacious in both stage 1 and stage 2 murine HAT models and has good physicochemical and ADMET properties for the treatment of stage 2 human African trypanosomiasis.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC8930	Rafoxanide	Rafoxanide is a salicylanilide used as an antiparasitic agent.
DC7791	NITD 609	NITD 609 is a novel and potent drug candidate for the treatment of uncomplicated malaria
DC10258	Mebendazole	Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking g
DC11738	SCYX-7158	An orally-active, CNS permeable benzoxaborole antiprotozoal agent.
DC11849	DSM421	A potent, selective P. falciparum dihydroorotate dehydrogenase (PfDHODH) with IC50 of 53 nM.