| Cas No.: | 1281861-06-0 |
| Chemical Name: | 2-(1,1-difluoroethyl)-5-methyl-N-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine |
| Synonyms: | DSM-421;DSM 421 |
| SMILES: | C12=NC(C(F)(F)C)=NN1C(NC1=CC=C(C(F)(F)F)C=C1)=CC(C)=N2 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A potent, selective P. falciparum dihydroorotate dehydrogenase (PfDHODH) with IC50 of 53 nM; does not inhibits human enzymes; inhibits Pf 3D7 with EC50 of 14 nM, has improved drug-like properties and better species selectivity relative to DSM265, whilst maintaining efficacy and pharmacokinetic properties . |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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