TAK-915
Cat. No.: DC11936
Chemical Structure
1476727-50-0
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Field of application
A highly potent, selective, brain-penetrating and orally active phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 0.61 nM.
| Cas No.: |
1476727-50-0 |
| Chemical Name: |
N-((1S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide |
| Synonyms: |
TAK915;TAK 915 |
| SMILES: |
C12=NC=C(OC)C=C1NC(=O)CN2C(N[C@H](C1=CC=C(OC(F)(F)F)C(F)=C1)COC)=O |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
A highly potent, selective, brain-penetrating and orally active phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 0.61 nM; dispalys 4100-fold selectivity over PDE1A, and >20,000-fold over other PDE isoforms; robustly increased cGMP levels in the rat brain, attenuates MK-801-induced episodic memory deficits in rats. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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