ODN 2006 Sodium |CAS 541547-35-7|DC Chemicals

Cas No.:	541547-35-7
Chemical Name:	ODN 2006 Sodium
SMILES:	O=C1N(C2CC(OP(=S)(OCC3C(OP(=S)(OCC4OC(N5C=NC6=C5N=C(NC6=O)N)CC4OP(=S)(OCC4OC(N5C(=O)NC(=O)C(C)=C5)CC4OP(=S)(OCC4C(OP(OCC5C(OP(=S)(OCC6C(OP(OCC7OC(N8C(=O)NC(=O)C(C)=C8)CC7O)([O-])=S)CC(N7C(=O)NC(=O)C(C)=C7)O6)[O-])CC(N6C7=C(C(=O)NC(N)=N7)N=C6)O5)([O-])=S)CC(N5C=CC(N)=NC5=O)O4)[O-])[O-])[O-])CC(N4C(=O)N=C(N)C(C)=C4)O3)[O-])C(COP(OC3CC(N4C=C(C)C(N)=NC4=O)OC3COP(=S)(OC3CC(N4C(=O)N=C(N)C(C)=C4)OC3COP(=S)(OC3CC(N4C=NC5=C4N=C(N)NC5=O)OC3COP(OC3CC(N4C=CC(N)=NC4=O)OC3COP(=S)(OC3CC(N4C(=O)NC(=O)C(C)=C4)OC3COP(OC3C(COP(OC4CC(N5C=C(C)C(=O)NC5=O)OC4COP(=S)(OC4C(COP(=S)(OC5C(COP(OC6CC(N7C(=O)N=C(N)C(C)=C7)OC6COP(OC6C(COP(OC7CC(N8C(=O)N=C(N)C=C8)OC7COP(OC7CC(N8C=C(C)C(=O)NC8=O)OC7COP(OC7C(COP(=S)(OC8C(COP(OC9CC(N%10C(=O)NC(=O)C(C)=C%10)OC9CO)([O-])=S)OC(N9C(=O)N=C(N)C=C9)C8)[O-])OC(N8C9=C(C(=O)NC(=N9)N)N=C8)C7)([O-])=S)([O-])=S)([O-])=S)OC(N7C=NC(C(NC(N)=C)=O)=C7C)C6)([O-])=S)([O-])=S)OC(N6C=C(C)C(N)=NC6=O)C5)[O-])OC(N5C=C(C)C(=O)NC5=O)C4)[O-])([O-])=S)OC(N4C=NC5=C4N=C(NC5=O)N)C3)([O-])=S)[O-])([O-])=S)[O-])[O-])([O-])=S)O2)C=C(C)C(N)=N1.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Formula:	C₂₃₈H₂₉₁N₇₅O₁₂₇P₂₃S₂₃-₂₃^.₂₃[Na+]
M.Wt:	8212.94
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC67268	ODN 21798 Sodium	Inducing the production of IFNα and the chemokine IP-10, stimulating immune cells to produce chemokines, and enhancing immune cell migration.
DC67267	CpG-ODN no.2 Sodium	Inducing a TH1-type immune response, enhancing IFN-γ production, activating TH1 cells, and strengthening cell-mediated immune responses.
DC67266	ODN 2216	ODN2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. ODN2216 induces high amounts of IFN-α and IFN-β. ODN 2216 induces IFN-α by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). ODN 2216 stimulates IFN-γ production in peripheral blood mononuclear cells (PBMC), which is indirect and mediated by IFN-α/β. ODN 2216 can activate NK cells and promote IFN-γ production of TCR-triggered CD4+ T cells. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 2216 sodium) that retains the same biological activity.
DC67265	ODN 2336	ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 2336 sodium) that retains the same biological activity.
DC67264	ODN SD-101 Sodium	Enhancing dendritic cell maturation, stimulating T cell proliferation, and inducing the production of pro-inflammatory factors, upregulating CD83 and CD86, and promoting the maturation of IFN-DC and IL4-DC.
DC67263	ODN D-SL03	ODN D-SL03 is a C class CpG oligonucleotides, can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN D-SL03 sodium) that retains the same biological activity.
DC67262	PD-ODN 2006×3 Sodium	Activating TLR9, inducing IL-6 secretion, and promoting the production of inflammatory factors through TLR9 activation.
DC67260	ODN YW07 Sodium	Activating canine splenocytes, enhancing anti-rabies virus antibody levels, stimulating specific immune responses, and boosting antibody production.
DC67261	ODN 2007	ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3'. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 2007 sodium) that retains the same biological activity.
DC67259	ODN 2006 Sodium	Agatolimod sodium (ODN 2006) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’.