ODN 2216 |CAS 332437-00-0|DC Chemicals

Cas No.:	332437-00-0
Chemical Name:	ODN 2216
SMILES:	[DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G)]
M.Wt:	6432.00
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC67273	ODN INH-1	ODN INH-1 is palindromic and a class R (‘restricted’) inhibitory ODN. ODN INH-1 is a potent inhibitor of TLR9-induced B cells and macrophages
DC67272	INH ODNIRS-869 Sodium
DC67271	ODN IH-18 Sodium
DC67270	INH ODN4347 Sodium
DC67269	INH ODN4348 Sodium
DC67268	ODN 21798 Sodium
DC67267	CpG-ODN no.2 Sodium
DC67266	ODN 2216	ODN?2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. ODN?2216 induces high amounts of IFN-α and IFN-β. ODN 2216 induces IFN-α by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). ODN 2216 stimulates IFN-γ production in peripheral blood mononuclear cells (PBMC), which is indirect and mediated by IFN-α/β. ODN 2216 can activate NK cells and promote IFN-γ production of TCR-triggered CD4+ T cells. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 2216 sodium) that retains the same biological activity.
DC67265	ODN 2336	ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 2336 sodium) that retains the same biological activity.
DC67264	ODN SD-101 Sodium