DM1-SMe|DM1-SSMe|CA 138148-68-2|DC Chemicals

Cas No.:	138148-68-2
Chemical Name:	DM1-SMe; DM1-SSMe; maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine.
Synonyms:	DM1-SMe; DM1-SSMe; maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine.
SMILES:	C[C@@H]1[C@@H]2C[C@](NC(O2)=O)(O)[C@H](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[C@@H](OC([C@@H](N(C(CCSSC)=O)C)C)=O)[C@@]4(C)C1O4)=O)=C(Cl)C(OC)=C3
Formula:	C₃₆H₅₀ClN₃O₁₀S₂
M.Wt:	784.37
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC).

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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