DY131|cas 95167-41-2|DC Chemicals

Cas No.:	95167-41-2
Chemical Name:	Benzoic acid, p-hydroxy-, (p-(diethylamino)benzylidene)hydrazide
Synonyms:	Benzoic acid,4-hydroxy-, 2-[[4-(diethylamino)phenyl]methylene]hydrazide;DY131;DY131,N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine;Gsk 9089;DY-131;GSK-9089;4-Hydroxybenzoic acid 2-[[4-(diethylamino)phenyl]methylene]hydrazide;(E)-N'-(4-(diethylamino)benzylidene)-4-hydroxybenzohydrazide;C18H21N3O2;5VWV92039E;GSK9089;N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine;DY 131;(E)-N'-[4-(Diethylamino)benzylidene]-4-hydroxybenzohydrazide;N'-{[4-(diethylamino)phenyl]methylidene}-4-hydroxybenzohydrazide;BDBM22439;HMS3677A06;HMS3413A06;Benzoic acid, p-hydroxy-, (p-(diethylamino)benzylidene)hydrazide;ZIN
SMILES:	O([H])C1C([H])=C([H])C(=C([H])C=1[H])C(N([H])/N=C(\[H])/C1C([H])=C([H])C(=C([H])C=1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=O
Formula:	C₁₈H₂₁N₃O₂
M.Wt:	311.3782
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

DY131, a selective ERRγ agonist, could potentiate the ERRγ-induced growth inhibition in LNCaP- ERRγ and DU145- ERRγ cells in a dose-dependent manner compared with respective parental cells. DY131 inhibited the growth of the ERα-positive endometrial cancer cells but promoted that of the ERα-negative cancer cells. DY131 had no effect on the structurally related receptors ERRα or the estrogen receptors alpha and beta (ERalpha/beta). DY131 appears to inhibit Smo signaling through a common binding site shared by previously reported Smo agonists and antagonists. For the detailed information of DY131, the solubility of DY131 in water, the solubility of DY131 in DMSO, the solubility of DY131 in PBS buffer, the animal experiment (test) of DY131, the cell expriment (test) of DY131, the in vivo, in vitro and clinical trial test of DY131, the EC50, IC50,and Affinity of DY131, Please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC70000	Lysyllysyllysine	Lysyllysyllysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles.
DC33580	DODMA	DODMA, also known as MBN 305A is a a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery
DC33636	DOTAP	DOTAP, also known as 1,2-Dioleoyl-3-trimethylammoniumpropane, is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in gene delivery vectors for gene ther
DC46471	RP101988	RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely.
DC45184	Hydrofurimazine	Hydrofurimazine is a NanoLuc substrate whose enhanced aqueous solubility allows delivery of higher doses to mice. Hydrofurimazine enables sensitive bioluminescence imaging for either prolonged light production of high sensitivity.
DC37901	PD-173212	PD-173212 is a small molecule N-type calcium channel blocker.
DC37333	N,N-Diethyl-p-toluamide	N,N-Diethyl-p-toluamide is a mosquito repellent.
DC37321	AI3-15902	AI3-15902 is a biochemical.
DC37283	Methyl phenylcarbamate	Methyl phenylcarbamate is a biochemical.
DC37252	Ampyrone	Ampyrone is a metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.