Desidustat|cas 1616690-16-4|DC Chemicals

Cas No.:	1616690-16-4
Chemical Name:	Desidustat
Synonyms:	Desidustat;Y962PQA4KS;1,2-dihydroquinoline-3-carbonyl]glycine;N-[1-(cyclopropylmethoxy)-4-hydroxy-2-oxo-;Desidustat [INN];BCP29692;ZB1514;A16921;2-(1-(cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid;2-[[1-(cyclopropylmethoxy)-4-hydroxy-2-oxoquinoline-3-carbonyl]amino]acetic acid;Glycine, N-((1-(cyclopropylmethoxy)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl)-;N-(1-(Cyclopropy
SMILES:	O(C([H])([H])C1([H])C([H])([H])C1([H])[H])N1C(C(C(N([H])C([H])([H])C(=O)O[H])=O)=C(C2=C([H])C([H])=C([H])C([H])=C12)O[H])=O
Formula:	C₁₆H₁₆N₂O₆
M.Wt:	332.3080
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC10339	Vadadustat	Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.
DC7486	PX-478 2HCL	PX-478 is an inhibitor of HIF-1a with an IC50 of 20-30μM enhances radiosensitivity of prostate carcinoma cells.
DC10464	PT2385	PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic activity.
DC8390	Oltipraz	Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3.
DC12043	KHS-101	KHS101 is a selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM).
DC8447	KC7F2	KC7F2 is a potent HIF-1 pathway inhibitor and that its potential as a cancer therapy agent warrants further study.
DC8617	JNJ-42041935	JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.
DC10825	IOX4	IOX4 is a potent inhibitor of PHD2 (IC50 = 1.6 nM).
DC8166	Molidustat(BAY 85-3934)	Hypoxia-inducible factor prolyl hydroxylase inhibitor
DC5193	Roxadustat(FG-4592)	FG-4592 is an HIF αprolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production.