Cas No.: | 1262770-73-9 |
Chemical Name: | KHS-101 free base |
Synonyms: | N4-isobutyl-N2-((2-phenylthiazol-4-yl)Methyl)pyriMidine-2,4-diaMine;N4-isobutyl-N2-[(2-phenylthiazol-4-yl)methyl]pyrimidine-2,4-diami ne |
SMILES: | CC(C)CN=C1C=CN=C(NCC2=CSC(=N2)C3=CC=CC=C3)N1 |
Formula: | C18H21N5S |
M.Wt: | 339.461 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo. |