Epithalon | Telomerase Activator

Cas No.:	307297-39-8
Chemical Name:	Epitalon
Synonyms:	Glycine, L-alanyl-L-a-glutamyl-L-a-aspartyl-;Epitalon;Epithalon;L-alanyl-L-alpha-glutamyl-L-alpha-aspartylglycine
SMILES:	OC(CNC([C@@H](NC([C@@H](NC([C@@H](N)C)=O)CCC(=O)O)=O)CC(=O)O)=O)=O
Formula:	C₁₄H₂₂N₄O₉
M.Wt:	390.3459
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Khavinson VKh. et al. Peptides and Ageing. Neuro Endocrinol Lett. 2002;23 Suppl 3:11-144. [2]. Vanhee C, et al. Identification of the small research tetra peptide Epitalon, assumed to be a potential treatment for cancer, old age and Retinitis Pigmentosa in two illegal pharmaceutical preparations. Drug Test Anal. 2015 Mar;7(3):259-64. [3]. Khavinson VKh, et al. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003 Jun;135(6):590-2.

Description:

Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa.

References:

[1]. Khavinson VKh. et al. Peptides and Ageing. Neuro Endocrinol Lett. 2002;23 Suppl 3:11-144. [2]. Vanhee C, et al. Identification of the small research tetra peptide Epitalon, assumed to be a potential treatment for cancer, old age and Retinitis Pigmentosa in two illegal pharmaceutical preparations. Drug Test Anal. 2015 Mar;7(3):259-64. [3]. Khavinson VKh, et al. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003 Jun;135(6):590-2.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC29105	Epithalon	Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa.
DC8861	2'-Deoxythioguanosine	6-thio-dG is a nucleoside analog and telomerase substrate.
DC11310	MST312	MST312 is a telomerase inhibitor (IC50 = 0.67 μM in a TRAP assay).
DC7085	BIBR-1532	BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM.