GKT136901|CAS 955272-06-7|DC Chemicals

Cas No.:	955272-06-7
Chemical Name:	2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo4,3-cpyridine-3,6(2H,5H)-dione
Synonyms:	2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione;AK120765;GKT136901;2-(2-Chlorophenyl)-4-methyl-5-(2-pyridinylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione (ACI);GKT 136901
SMILES:	O=C1N(CC2C=CC=CN=2)C(C)=C2C(NN(C3C(Cl)=CC=CC=3)C2=O)=C1
Formula:	C₁₉H₁₅ClN₄O₂
M.Wt:	366.80100274086
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

MSDS

COA

Cat. No.	Product name	Field of application
DC40030	GKT136901	GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 also is a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity.
DC11809	APX-115	APX-115 (Ewha 18278) is a first-in-class, orally active, pan-NADPH oxidase (Nox) inhibitor with Ki of 1.08, 0.57, 0.63 nM for Nox1, Nox2, and Nox4, respectively.