| DC47011 |
Elinzanetant
|
Elinzanetant is a neurokinin receptors antagonist used for the research of Schizophrenia. |
| DC46851 |
Imnopitant
|
Imnopitant is a NK1 receptor antagonist (WO2020132716, compound 1) . |
| DC46850 |
SB 218795
|
SB 218795 is a potent and selective non-peptide NK3 receptor antagonist, with a Ki 13 nM for hNK3. SB 218795 shows about 90-fold and 7000-fold selectivity for hNK3 over hNK2 and hNK1, respectively. SB 218795 can inhibit NK3 receptor-mediated pupillary constriction of the rabbit. |
| DC42312 |
Hemokinin 1 (mouse)
|
Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively. |
| DC42311 |
Neurokinin A TFA
|
Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues. |
| DC42048 |
Biotin-Substance P
|
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). |
| DC41718 |
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA
|
[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM. |
| DC41717 |
[Lys5,MeLeu9,Nle10]-NKA(4-10)
|
[Lys5,MeLeu9,Nle10]-NKA(4-10) is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM. |
| DC41716 |
GR 64349 TFA
|
GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively. |
| DC41715 |
GR 94800 TFA
|
GR 94800 TFA is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively. |
