HBX 41108|cas 924296-39-9|DC Chemicals

Cas No.:	924296-39-9
Chemical Name:	7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile;7-Chloro-9-oxo-9H-indeno[1,2-b]-pyrazine-2,3-dicarbonitrile;7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile DISCONTINUED;HBX 41108
Synonyms:	7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile;7-Chloro-9-oxo-9H-indeno[1,2-b]-pyrazine-2,3-dicarbonitrile;7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile DISCONTINUED;HBX 41108
SMILES:	C1=CC2=C(C=C1Cl)C(=O)C3=C2N=C(C#N)C(=N3)C#N
Formula:	C₁₃H₃N₄OCl
M.Wt:	266.64212
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. For the detailed information of HBX41108 , the solubility of HBX41108 in water, the solubility of HBX41108 in DMSO, the solubility of HBX41108 in PBS buffer, the animal experiment (test) of HBX41108 , the cell expriment (test) of HBX41108 , the in vivo, in vitro and clinical trial test of HBX41108 , the EC50, IC50,and affinity,of HBX41108 , For the detailed information of HBX41108 , the solubility of HBX41108 in water, the solubility of HBX41108 in DMSO, the solubility of HBX41108 in PBS buffer, the animal experiment (test) of HBX41108 , the cell expriment (test) of HBX41108 , the in vivo, in vitro and clinical trial test of HBX41108 , the EC50, IC50,and affinity,of HBX41108 , Please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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