| Cas No.: | 914638-30-5 |
| Chemical Name: | IDO-IN1 |
| Synonyms: | (Z)-4-amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide;4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide;(E)-4-amino-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide;4-amino-N(3-bromo-4-fluorophenyl)-N-hydroxy-;IDO-IN-1;IDO-IN1 |
| SMILES: | NC1=NON=C1/C(NO)=N/C2=CC(Br)=C(F)C=C2 |
| Formula: | C9H7BrFN5O2 |
| M.Wt: | 316.086583375931 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM. |
| In Vitro: | IDO-IN-1 (Compound 5m) is a potent (HeLa IC50=12 nM) inhibitor of IDO[1]. |
| References: | [1]. Yue EW, et al. Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem. 2009 Dec 10;52(23):7364-7. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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