Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Indoleamine 2,3-Dioxygenase (IDO)

BMS-986205(Linrodostat)

  Cat. No.:  DC10131   Featured
Chemical Structure
1923833-60-6
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More than 5000 active chemicals with high quality for research!
Field of application
BMS-986205 is an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic activity, alone and in combination with nivolumab in advanced cancers in a phase 1/2a trial
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1923833-60-6
Chemical Name: BMS-986205
Synonyms: Linrodostat;BMS986205;(R)-N-(4-chlorophenyl)-2-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide;0A7729F42K;Linrodostat (USAN);(2R)-N-(4-chlorophenyl)-2-[cis-4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide;C24H24ClFN2O;GTPL9707;ONO 7701;BDBM50285416;NSC799771;s8629;BMS
SMILES: ClC1C=CC(=CC=1)NC([C@H](C)C1CCC(C2C=CN=C3C=CC(=CC=23)F)CC1)=O
Formula: C24H24ClFN2O
M.Wt: 410.9116
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: BMS-986205 is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC10098 IDO-IN-1 IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM).
DC10131 BMS-986205(Linrodostat) BMS-986205 is an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic activity, alone and in combination with nivolumab in advanced cancers in a phase 1/2a trial
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