| DC46171 |
PROTAC IRAK4 degrader-5
|
PROTAC IRAK4 degrader-5 is a PROTAC-based IRAK4 degrader extracted from patent US20190192668A1, compound I-171. |
| DC42505 |
IRAK-4 protein kinase inhibitor 2
|
IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disorders. |
| DC42322 |
HS271
|
HS271 is a highly potent, orally active and selective IRAK4, with an IC50 of 7.2 μM. HS271 exhibits superior enzymatic and cellular activities, as well as excellent pharmacokinetic properties. |
| DC40577 |
IRAK inhibitor 4
|
IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4(IRAK4) inhibitor. |
| DC40037 |
JH-X-119-01 hydrochloride
|
JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice. |
| DC28331 |
IRAK4-IN-4
|
IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM. |
| DC11185 |
PF-06426779
|
PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM. |
| DC9492 |
IRAK inhibitor 2
|
IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
| DC11497 |
IRAK4-IN-28
|
A novel potent, selective IRAK4 inhibitor with IC50 of 51 nM. |
