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KBU2046

  Cat. No.:  DC10852   Featured
Chemical Structure
1143863-69-7
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More than 5000 active chemicals with high quality for research!
Field of application
KBU2046, is a small molecule that attaches to tumor proteins involved in metastasis and disables them, so they can’t travel to distant organs.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1143863-69-7
Chemical Name: 3-(4-Fluorophenyl)chroman-4-one
Synonyms: KBU2046;3-(4-Fluorophenyl)chroman-4-one;3-(4-Fluoro-phenyl)-chroman-4-one;4'-fluoroisoflavanone;KBU 2046;KBU2046,;BDBM50445506;3-(4-fluorophenyl)-2,3-dihydrochromen-4-one
SMILES: FC1C([H])=C([H])C(=C([H])C=1[H])C1([H])C(C2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])=O
Formula: C15H11FO2
M.Wt: 242.2450
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: KBU2046 is an oral, highly selective inhibitor of cell motility and cell invasion in vitro. KBU2046 binds chaperone heterocomplexes, selectively alters binding of client proteins that regulate motility, and lacks all of the hallmarks of classical HSP90 inhibitors. KBU2046 inhibits cancer metastasis and prolongs life[1].
References: [1]. Xu L, et al. Precision therapeutic targeting of human cancer cell motility. Nat Commun. 2018 Jun 22;9(1):2454.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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