Cas No.: | 790-69-2 |
Chemical Name: | loflucarban |
Synonyms: | Thiourea,N-(3,5-dichlorophenyl)-N'-(4-fluorophenyl)-;1-(3,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea;3,5-Dichloro-4'-fluorothiocarbanilide;Fluonilid;Fluonilide;Fluoro-4-dichloro-3',5'-thiocarbanilide;Loflucarban;Loflucarbanum;Loflucarbanum [Latin] |
SMILES: | FC1=CC=C(NC(NC2=CC(Cl)=CC(Cl)=C2)=S)C=C1 |
Formula: | C13N2FScl2H9 |
M.Wt: | 315.1934 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Loflucarban (Fluonilid) is a potent antimycotic agent. Loflucarban can be used for the research of the ear infections[1]. |
In Vitro: | One hundred-and-eighty-six fungi were isolated from one hundred-and-eighty cases diagnosed as otomycosis. They comprise 59 species of 26 genera of moulds, and 2 genera of yeasts. Fluonilid shows the MIC ranged from > 100 μg/ml to 1 μg/ml for the majority of tested fungi[1]. |
References: | [1]. Maher A, et al. Otomycosis: an experimental evaluation of six antimycotic agents. J Laryngol Otol. 1982;96(3):205-213. |