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Home > Inhibitors & Agonists > NF-κB Pathway > MALT1

MLT-231

  Cat. No.:  DC42356   Featured
Chemical Structure
2682102-10-7
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Field of application
MLT-231 is a potent, highly selective allosteric MALT1 with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2682102-10-7
Chemical Name: MLT-231
SMILES: O=C(NC1=C(N2[C@@H](C)COC[C@@H]2C)N3C(N=C1)=CC(Cl)=N3)NC4=CC=NC(C(F)(F)F)=C4
Formula: C19H19ClF3N7O2
M.Wt: 469.85
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_25963_DC42356
COA
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Cat. No. Product name Field of application
DC48250 MLT-985 MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.
DC42356 MLT-231 MLT-231 is a potent, highly selective allosteric MALT1 with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse.
DC7621 MI 2 (Menin-MLL Inhibitor) MI-2 is an inhibitor of MALT1 with IC50 value of 5.84 μM.
DC9503 MI 2 (MALT1 inhibitor) MI 2(MALT1 inhibitor) is a small molecule and irreversible inhibitor of MALT1 with IC50 of 5.84 uM(suppression of proliferation in ABCDLBCL).
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