MLT-985

  Cat. No.:  DC48250   Featured
Chemical Structure
1832576-25-6
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Field of application
MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.
Cas No.: 1832576-25-6
Chemical Name: Urea, N-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-N'-[5-chloro-6-(2H-1,2,3-triazol-2-yl)-3-pyridinyl]-
Synonyms: Urea, N-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-N'-[5-chloro-6-(2H-1,2,3-triazol-2-yl)-3-pyridinyl]-;MLT-985
SMILES: N(C1=C([C@@H](OC)C)N2N=C(Cl)C=C2N=C1)C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)=O
Formula: C17H15Cl2N9O2
M.Wt: 448.27
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_32141_DC48250_1832576-25-6
COA
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Cat. No. Product name Field of application
DC48250 MLT-985 MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.
DC42356 MLT-231 MLT-231 is a potent, highly selective allosteric MALT1 with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse.
DC7621 MI 2 (Menin-MLL Inhibitor) MI-2 is an inhibitor of MALT1 with IC50 value of 5.84 μM.
DC9503 MI 2 (MALT1 inhibitor) MI 2(MALT1 inhibitor) is a small molecule and irreversible inhibitor of MALT1 with IC50 of 5.84 uM(suppression of proliferation in ABCDLBCL).
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