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Quinupristin

  Cat. No.:  DC12365   Featured
Chemical Structure
120138-50-3
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More than 5000 active chemicals with high quality for research!
Field of application
Quinupristin/dalfopristin, or quinupristin-dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 120138-50-3
Chemical Name: N-[(4-dimethylaminophenyl)methyl-ethyl-dimethyl-heptaoxo-phenyl-[[(3S)-quinuclidin-3-yl]sulfanylmethyl][?]yl]-3-hydroxy-pyridine-2-carboxamide
SMILES: CCC1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3C[C@H](C(=O)CC3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CS[C@@H]6CN7CCC6CC7)CC8=CC=C(C=C8)N(C)C)C
Formula: C53H67N9O10S
M.Wt: 1022.232
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].
In Vitro: Quinupristin/dalfopristin is a combination of streptogramin antibiotics used to against infections.Quinupristin/dalfopristin targets the 23S rRNA of most Gram-positive bacteria as well as those of certain Gram-negative bacteria[1]. Quinupristin/dalfopristin is reportedly effective against Mycoplasma spp[1].
References: [1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6. [2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3).
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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