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RBPJ Inhibitor-1

  Cat. No.:  DC41036  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Chemical Name: RBPJ Inhibitor-1
SMILES: O=C(N)C1=CC=C(C2=CC=NN2C)C=C1OC3=CC=CC=C3F
Formula: C17H14FN3O2
M.Wt: 311.31
Sotrage: Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month
MSDS
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MSDS_24049_DC41036
COA
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Cat. No. Product name Field of application
DC46594 SAHM1 TFA SAHM1 TFA is a Notch pathway inhibitor. SAHM1 TFA stabilizes hydrocarbon-stapled alpha helical peptide. SAHM1 TFA targets the protein-protein interface and prevents Notch complex assembly.
DC46314 Notch 1 TFA Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types.
DC41036 RBPJ Inhibitor-1 RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation.
DC11930 EDD3 A novel Notch inhibitor that reduces protein expression of NOTCH1, NICD and HES1 in HEK293 cells and downregulates Notch target genes.
DC11489 6-alkynyl Fucose A fucose analog that inhibits Dll-induced Notch signaling by reducing Notch ligand Dll1-Notch1 binding, but not Jag1.
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