Cas No.: | 1174161-86-4 |
Chemical Name: | BMS-817378 |
Synonyms: | SCR1481B1,BMS-817378,BMS817378,BMS 817378 |
SMILES: | O=C(C1=CN(COP(O)(O)=O)C=C(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C(Cl)C(N)=NC=C4)C(F)=C3.OCC(CO)(N)CO |
Formula: | C31H35ClF2N5O10P |
M.Wt: | 742.067 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor. |
Target: | VEGFR1 |
In Vitro: | More details please refer to Patent WO 2009094417 A1. |
References: | [1]. Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1. |