Verinurad
Cat. No.: DC10029
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Chemical Structure
1352792-74-5
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Field of application
Verinurad is an urate transporter inhibitor with EC50 value of 0.05 μM.Verinurad is useful in the modulation of blood or serum uric acid levels, reducing serum uric acid levels in a human.
| Cas No.: |
1352792-74-5 |
| SMILES: |
CC(C)(C(=O)O)SC1=C(C=NC=C1)C2=CC=C(C3=CC=CC=C32)C#N |
| Formula: |
C20H16N2O2S |
| M.Wt: |
348.42 |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC50 of 25 nM[1]. |
| Target: |
IC50: 25 nM (URAT1)[1] |
| In Vitro: |
Verinurad inhibits the transport activity of human URAT1 in a dose-dependent manner, at high potency with an IC50 of 25 nM [1]. |
| References: |
[1]. Tan PK, et al. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Sci Rep. 2017 Apr 6;7(1):665. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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