Cas No.: | 1352792-74-5 |
SMILES: | CC(C)(C(=O)O)SC1=C(C=NC=C1)C2=CC=C(C3=CC=CC=C32)C#N |
Formula: | C20H16N2O2S |
M.Wt: | 348.42 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC50 of 25 nM[1]. |
Target: | IC50: 25 nM (URAT1)[1] |
In Vitro: | Verinurad inhibits the transport activity of human URAT1 in a dose-dependent manner, at high potency with an IC50 of 25 nM [1]. |
References: | [1]. Tan PK, et al. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Sci Rep. 2017 Apr 6;7(1):665. |