Voriconazole
Cat. No.: DCAPI1451
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Chemical Structure
137234-62-9
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Field of application
Voriconazole is an ergosterol biosynthesis inhibitor, as well as systemic antifungal. This compound, like many antifungal agents, is an inhibitor of CYP2C9, an enzyme involved in the oxidative metabolism of many xenobiotics.
Cas No.: |
137234-62-9 |
SMILES: |
FC1=CC=C([C@@]([C@H](C2=NC=NC=C2F)C)(O)CN3N=CN=C3)C(F)=C1 |
Formula: |
C16H14F3N5O |
M.Wt: |
349.31 |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
Voriconazole(UK-109496) is a second-generation triazole antifungal used to treat serious fungal infections.IC50 Value: Target: AntifungalVoriconazole displays potent activity against Candida, Cryptococcus and Aspergillus species. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes |
MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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2018-0101 |
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