Cas No.: | 137234-62-9 |
SMILES: | FC1=CC=C([C@@]([C@H](C2=NC=NC=C2F)C)(O)CN3N=CN=C3)C(F)=C1 |
Formula: | C16H14F3N5O |
M.Wt: | 349.31 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Voriconazole(UK-109496) is a second-generation triazole antifungal used to treat serious fungal infections.IC50 Value: Target: AntifungalVoriconazole displays potent activity against Candida, Cryptococcus and Aspergillus species. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes |