Cas No.: | 853220-52-7 |
Chemical Name: | BML 284; BML284;BML-284 |
Synonyms: | BML 284; BML284;BML-284 |
SMILES: | NC1=NC(C2=CC=CC(OC)=C2)=CC(NCC3=CC=C(OCO4)C4=C3)=N1 |
Formula: | C19H18N4O3 |
M.Wt: | 350.37 |
Sotrage: | 4°C for 1 year, -20°C for more than 2 years |
Publication: | A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy.-DOI:https://doi.org/10.1016/j.xcrm.2020.100122 |
Description: | AMBMP(BML-284) is potent selective, and cell-permeable Wnt signaling activator.in vitro: BML-284 induces the β-catenin/TCF-dependent reporter in a dose-dependent manner. |
In Vitro: | BML-284 appears to mimic the effects of a Wnt ligand in a Xenopus model and may be a useful tool in the study of physiological processes that involve the Wnt pathway. |