CC-99677
Cat. No.: DC46922
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Chemical Structure
1887069-10-4
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Field of application
CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM).
Cas No.: |
1887069-10-4 |
Chemical Name: |
CC-99677 |
Synonyms: |
(10R)-3-[[2-Chloro-5-(ethoxymethyl)-4-pyrimidinyl]oxy]-9,10,11,12-tetrahydro-10-methyl-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one |
SMILES: |
N1[C@@H](CNC2C3=C(C=CC4=NC(OC5C(COCC)=CN=C(Cl)N=5)=CC=C34)SC=2C1=O)C |
Formula: |
C22H20ClN5O3S |
M.Wt: |
469.94 |
Purity: |
98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
COA
LOT NO. |
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2018-0101 |
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