Zunsemetinib|CAS 1640282-42-3|DC Chemicals

Cas No.:	1640282-42-3
Chemical Name:	Zunsemetinib
Synonyms:	zunsemetinib;AX2VWG0ZCR;Zunsemetinib [INN];Zunsemetinib [USAN];ATI450;CDD450;GTPL11681;BDBM175242;WHO 11983;US9115089, 49;(1(2H),4'-Bipyridin)-2-one, 3-chloro-4-((3,5-difluoro-2-pyridinyl)methoxy)-2'-(2-(1-hydroxy-1-methylethyl)-4-pyrimidinyl)-5',6-dimethyl-, (-)-;(p)-3-Chloro-4-((3,5-difluoropyridin-2-yl)methoxy)-2'-(2-(2-hydroxypropan-2-yl)pyrimidin-4-yl)-5',6-dimethyl-2H-(1,4'-bipyridin)-2-one;3-chloro-4-[(3,5-difluoro
SMILES:	ClC1=C(C([H])=C(C([H])([H])[H])N(C1=O)C1=C([H])C(C2C([H])=C([H])N=C(C(C([H])([H])[H])(C([H])([H])[H])O[H])N=2)=NC([H])=C1C([H])([H])[H])OC([H])([H])C1=C(C([H])=C(C([H])=N1)F)F
Formula:	C₂₅H₂₂ClF₂N₅O₃
M.Wt:	513.9237
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC47260	Zunsemetinib	Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases.
DC46922	CC-99677	CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM).