CCT241950

  Cat. No.:  DC73199  
Chemical Structure
1213785-29-5
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More than 5000 active chemicals with high quality for research!
Field of application
CCT241950 (CCT 241950) is a small molecule NEK2 inhibitor, induces Tyr70Nek2 to jut into the ADP-binding pocket.
Cas No.: 1213785-29-5
Chemical Name: CCT241950
Formula: C21H20N2O5
M.Wt: 380.4
MSDS
Cat. No. Product name Field of application
DC73200 T-1101 tosylate T-1101 tosylate (TAI-95 tosylate) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
DC73199 CCT241950 CCT241950 (CCT 241950) is a small molecule NEK2 inhibitor, induces Tyr70Nek2 to jut into the ADP-binding pocket.
DC70138 Nek2 inhibitor 3a A potent, relatively selective Nek2 inhibitor with IC50 of 82.74 nM in cell-free assays; inhibits only 3 kinases (YSK4, FLT3-ITDD835V and FLT3-ITDF691L) against 97 kinases with >65% inhibition at 15 nM; blocks NEK2-EZH2 complex formation and inhibits tumor cell proliferation; efficiently attenuates GBM growth in mouse model and exhibits a synergistic effect with radiotherapy.
DC70137 Nek2 inhibitor 11 A potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.67 uM; displays >10-fold selectivity over CDK2.
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