Cilofexor
Cat. No.: DC10868
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Chemical Structure
1418274-28-8
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Field of application
Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
| Cas No.: |
1418274-28-8 |
| Chemical Name: |
Cilofexor |
| Synonyms: |
Cilofexor;PX104;YUN2306954;GS 9674;2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid;2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid;Cilofexor [INN];Cilofexor (GS(c)\\9674);GTPL10644;BCP29283;BDBM50511109;GS9674;s6547;DB15168;example 13/9 [US1 |
| SMILES: |
ClC1C([H])=C(C([H])=C([H])C=1C1(C([H])([H])N(C2C([H])=C(C(=O)O[H])C([H])=C([H])N=2)C1([H])[H])O[H])OC([H])([H])C1C(C2C(=C([H])C([H])=C([H])C=2Cl)Cl)=NOC=1C1([H])C([H])([H])C1([H])[H] |
| Formula: |
C28H22Cl3N3O5 |
| M.Wt: |
586.8504 |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
Cilofexor is a farnesoid X receptor (FXR) agonist. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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