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CMX-2043

  Cat. No.:  DC72496  
Chemical Structure
910627-26-8
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More than 5000 active chemicals with high quality for research!
Field of application
CMX-2043 is a novel analogue of α-Lipoic Acid. CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 910627-26-8
Chemical Name: CMX-2043
SMILES: C[C@H](NC([C@@H](NC(CCCC[C@H]1SSCC1)=O)CCC(O)=O)=O)C(O)=O
Formula: C16H26N2O6S2
M.Wt: 406.52
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36947_DC72496_910627-26-8
COA
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Cat. No. Product name Field of application
DC72496 CMX-2043 CMX-2043 is a novel analogue of α-Lipoic Acid. CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model.
DC71094 NT219 NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases.
DC71030 Demethylasterriquinone B1 Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT.
DC50119 AVJ16 AVJ16 is a member of the insulin-like growth factor 2 mRNA-binding protein family. AVJ16 regulates protein translation by binding to the mRNAs of certain genes.
DC50118 HNMPA-(AM)3 HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis.
DC49413 Insulin glargine Insulin glargine is a long-acting insulin analog. Insulin glargine can be used for the diabetes mellitus.
DC48362 OI338 OI338 is an orally available, ultralong-acting insulin analogue.
DC47979 HNMPA HNMPA is a membrane impermeable insulin receptor tyrosine kinase inhibitor. HNMPA inhibits serine and tyrosine autophosphorylation by the human insulin receptor. HNMPA has no effect on protein kinase C or cyclic AMP-dependent protein kinase activities
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