CVN766

  Cat. No.:  DC73482   Featured
Chemical Structure
1803557-42-7
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More than 5000 active chemicals with high quality for research!
Field of application
CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
Cas No.: 1803557-42-7
Chemical Name: CVN766
SMILES: CCC1=NC(C(F)(F)F)=CN=C1N[C@@H]2[C@@H](NC(C3=NC=CC=C3N4N=CC=N4)=O)CCC2
Formula: C20H21F3N8O
M.Wt: 446.44
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC73482 CVN766 CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
DC71983 Nivasorexant Nivasorexant is a potent orexin receptor antagonist.
DC28246 EMPA EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively.
DC9573 SB-674042 SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.
DC7277 SB-408124 SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively; exhibits 50-fold selectivity over OX2 receptor.
DC8419 SB-334867 SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
DC7495 SB-334867 HCl SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2.
DC11439 Nemorexant ACT-541468 is a dual orexin receptor antagonist.
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