Nivasorexant|CAS 1435480-40-2|DC Chemicals

Cas No.:	1435480-40-2
Chemical Name:	Nivasorexant
Synonyms:	CHEMBL3892369;US9150566, 27;(4(3)R)-6-methyl-4(3,4)-morpholina-1,7(2)-di[1,2,3]triazola-2(1,3),6(1,2)-dibenzenaheptaphan-5-one;nivasorexant [INN];AT37341;Methanone, [4-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl][(3R)-3-[[3-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-4-morpholinyl]-;(4-Methyl-2-[1,2,3]triazol-2-ylphenyl)-[(R)-3-(3-[1,2,3]triazol-2-ylbenzyl)-morpholin-4-yl]-methanone;ACT-539313;(4-Methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)((3R)-3-((3-(2H-1,2,3-triazol-2-yl)phenyl)methyl)-4-morpholinyl)methanone;BDBM183990;0N15II81VX;Nivasorexant;HY-147294;SCHEMBL14940548;ACT539313;[4-methyl-2-(triazol-2-yl)phenyl]-[(3R)-3-[[3-(triazol-2-yl)phenyl]methyl]morpholin-4-yl]methanone;CS-0564145;GTPL12719;4-(4-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl)-3-((3-(2H-1,2,3-triazol-2-yl)phenyl)methyl)morpholine, (3R)-;1435480-40-2;UNII-0N15II81VX;nivasorexant
SMILES:	O1CCN(C(C2=CC=C(C)C=C2N2N=CC=N2)=O)[C@@H](C1)CC1C=CC=C(C=1)N1N=CC=N1
Formula:	C₂₃H₂₃N₇O₂
M.Wt:	429.474423646927
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC73482	CVN766	CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
DC71983	Nivasorexant	Nivasorexant is a potent orexin receptor antagonist.
DC28246	EMPA	EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively.
DC9573	SB-674042	SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.
DC7277	SB-408124	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively; exhibits 50-fold selectivity over OX2 receptor.
DC8419	SB-334867	SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
DC7495	SB-334867 HCl	SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2.
DC11439	Nemorexant	ACT-541468 is a dual orexin receptor antagonist.